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David H Margolin Selected Research

Alemtuzumab (Campath)

1/2021Efficacy and safety of alemtuzumab over 6 years: final results of the 4-year CARE-MS extension trial.
11/2020Efficacy of alemtuzumab over 6 years in relapsing-remitting multiple sclerosis patients who relapsed between courses 1 and 2: Post hoc analysis of the CARE-MS studies.
10/2020Proportion of alemtuzumab-treated patients converting from relapsing-remitting multiple sclerosis to secondary progressive multiple sclerosis over 6 years.
1/2020Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management.
1/2020Impact of alemtuzumab on health-related quality of life over 6 years in CARE-MS II trial extension patients with relapsing-remitting multiple sclerosis.
10/2019Infection risk with alemtuzumab decreases over time: pooled analysis of 6-year data from the CAMMS223, CARE-MS I, and CARE-MS II studies and the CAMMS03409 extension study.
1/2019Incidence, management, and outcomes of autoimmune nephropathies following alemtuzumab treatment in patients with multiple sclerosis.
9/2017Alemtuzumab CARE-MS II 5-year follow-up: Efficacy and safety findings.
9/2017Alemtuzumab improves quality-of-life outcomes compared with subcutaneous interferon beta-1a in patients with active relapsing-remitting multiple sclerosis.
11/2016Alemtuzumab improves preexisting disability in active relapsing-remitting MS patients.
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David H Margolin Research Topics

Disease

20Relapsing-Remitting Multiple Sclerosis
01/2021 - 10/2008
13Multiple Sclerosis
11/2020 - 10/2008
5Infections
01/2021 - 10/2008
5Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2020 - 10/2008
2Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome)
01/2019 - 01/2013
1Schizophrenia (Dementia Praecox)
01/2022
1Psychotic Disorders (Schizoaffective Disorder)
01/2022
1Parkinson Disease (Parkinson's Disease)
01/2022
1Chronic Progressive Multiple Sclerosis
10/2020
1Membranous Glomerulonephritis (Membranous Nephropathy)
01/2019
1Atrophy
09/2017
1Hypothyroidism
01/2014
1Subacute Thyroiditis (Thyroiditis, De Quervain)
01/2014
1Hyperthyroidism
01/2014
1Papillary Carcinoma
11/2012
1Pathologic Complete Response
12/2011
1Hypogonadism (Hypergonadotropic Hypogonadism)
04/2002
1Dementia (Dementias)
04/2002
1Ataxia (Dyssynergia)
04/2002

Drug/Important Bio-Agent (IBA)

21Alemtuzumab (Campath)FDA Link
01/2021 - 10/2008
14Interferon beta-1aFDA Link
01/2021 - 10/2008
5Monoclonal AntibodiesIBA
07/2015 - 10/2008
2Inosine Triphosphate (ITP)IBA
01/2020 - 12/2011
2InterferonsIBA
10/2016 - 04/2011
1Antipsychotic Agents (Antipsychotics)IBA
01/2022
1Serotonin (5 Hydroxytryptamine)IBA
01/2022
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2022
1Pharmaceutical PreparationsIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
01/2022
1Acyclovir (Aciclovir)FDA LinkGeneric
10/2019
1Cytidine Diphosphate (CDP)IBA
01/2019
1antiglomerular basement membrane antibodyIBA
01/2019
1Interferon-betaIBA
11/2012
1Glatiramer Acetate (Copaxone)FDA Link
11/2012
1GonadotropinsIBA
04/2002
1SteroidsIBA
04/2002

Therapy/Procedure

10Therapeutics
01/2020 - 10/2008
1Retreatment
10/2019
1Off-Label Use
01/2019
1Intravenous Infusions
07/2015